Alzheimer’s has long been considered irreversible, but new research challenges that assumption. Scientists discovered that severe drops in the brain’s energy supply help drive the disease—and ...

When scientists opened the doors of a research facility and let carefully bred lab mice loose into a fenced field, they ...

Researchers have developed a gene-editing treatment for prion disease that extends lifespan by about 50 percent in a mouse model of the fatal neurodegenerative condition. The treatment, which uses ...

In recent months, the Food and Drug Administration and National Institutes of Health have announced new initiatives to reduce and replace animal testing in biomedical research. Central to these ...

Researchers at the Jan and Dan Duncan Neurological Research Institute (NRI) at Texas Children’s Hospital and Baylor College of Medicine recently made an important advance in neurodegenerative disease ...

For generations, laboratory mice have lived and died under fluorescent lights, their world reduced to plastic cages and ...

In the wild, a mouse or rat leads a precarious life. In the city, they dodge traps, poisons, and broom-wielding humans. In the countryside, they face owls, shotguns, and more poison. As Australia’s ...

Experimental drug NU-9 shows promise in clearing toxic proteins associated with neurodegenerative diseases. Scientists tested NU-9 in a pre-symptomatic animal model of Alzheimer’s disease. Drug ...