How does the cell convert DNA into working proteins? The process of translation can be seen as the decoding of instructions for making proteins, involving mRNA in transcription as well as tRNA. But ...
This is a summary of: Liu. H. et al. Viral RNA blocks circularization to evade host codon usage control. Nature https://doi.org/10.1038/s41586-025-09809-y (2025).
Transcription and translation are processes a cell uses to make all proteins the body needs to function from information stored in the sequence of bases in DNA. The four bases (C, A, T/U, and G in the ...
A virus relies on the host's translation machinery to replicate itself and become infectious. Translation efficiency ...
The genome contains all of the instructions a cell needs to build an organism. In coding regions of the genome, genes are transcribed into a molecule called mRNA, which is processed and then ...
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DeepCodon: A rare-codon–aware AI tool boosts protein expression in E. coli
A research team has developed DeepCodon, a deep learning–based codon optimization tool that significantly improves heterologous protein expression in Escherichia coli while preserving functionally ...
Nascent polypeptide chains or polypeptidyl-tRNAs (pep-tRNAs) occur transiently during protein synthesis. The potential to study these intermediates and better understand their role in processes like ...
Translation is the process that makes a protein based on messenger RNA Researchers now have a 3D structure for the complex that scans mRNA to start making protein Understanding how translation begins ...
The virusoid associated with rice yellow mottle virus encodes its own proteins; is it the exception that proves the rule, or the first of many more to come? It’s axiomatic in reviews of virusoids that ...
61 codons specify one of the 20 amino acids that make up proteins 3 codons are stop codons, which signal the termination of protein synthesis Importantly, the genetic code is nearly universal, shared ...
A study conducted by researchers at Ohio State University and the New York University Grossman School of Medicine in the USA, has revealed that optimization of codon for bacterial expression causes ...
A virus relies on the host's translation machinery to replicate itself and become infectious. Translation efficiency ...
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