Aug 4, 2025 · Aging triggers cellular senescence through multiple mechanisms such as DNA damage and oxidative stress.

The successive shortening of the chromosomal telomeres with each cell cycle is also believed to limit the number of divisions of the cell, contributing to aging.

Here we review a number of crucial processes responsible for regulating cellular health in aging and the link between many of those diseases and aging.

Dec 8, 2025 · Aging results from several factors, including genetics, our environment, and cellular damage. Genetic components, such as telomeres, influence lifespan. Oxidative stress and lifestyle …

Oxidative stress, cellular senescence, sustained inflammation, and DNA damage are the main cellular processes characteristic of aging associated with morphological and functional decline.

Jan 3, 2023 · That said, both in laboratory animals and in human medicine, objective quantification of morphological and functional decline affecting the aging organism is essential to measure biological …

Jul 28, 2025 · Cellular aging is a natural biological process where individual cells gradually lose their ability to function optimally over time. This decline is observed across all living organisms, involving …

May 8, 2024 · The term ‘aging’ encompasses the overall process of becoming older, including the physical and mental decline in our health. Senescence, however, refers to the aging process on a …

Mar 29, 2022 · When a single cell malfunctions, it can potentially harm the whole multicellular organism. There are two ways of controlling such incidences. The first is based on the ability of specialised …

Jul 7, 2023 · Here, we examine the fundamentals of aging and the hallmark of aging to explain the cellular and molecular-level alterations related to aging. For understanding the mechanism of cellular …